Corticosteroid-sparing effect of rifaximin, a nonabsorbable oral antibiotic, in active ulcerative colitis: Preliminary clinical experience
نویسندگان
چکیده
منابع مشابه
Corticosteroid Treatment of Ulcerative Colitis
ULCERATIVE COLITIS is a diffuse inflammatory disease of a part or the whole of the colon, the atiology of which is at present ill-understood. Medical treatment has, therefore, depended upon the application of general medical measures to combat the effects of the disease, together with the use of agents to diminish the inflammatory process. In the absence of precise atiological knowledge, the se...
متن کاملTofacitinib, an oral Janus kinase inhibitor, in active ulcerative colitis.
BACKGROUND Ulcerative colitis is a chronic inflammatory disease of the colon for which current treatments are not universally effective. One additional treatment may be tofacitinib (CP-690,550), an oral inhibitor of Janus kinases 1, 2, and 3 with in vitro functional specificity for kinases 1 and 3 over kinase 2, which is expected to block signaling involving gamma chain-containing cytokines inc...
متن کاملOral fluticasone propionate in active distal ulcerative colitis.
Fluticasone propionate is a new corticosteroid with low systemic bioavailability. This study reports the outcome of a double blind clinical trial comparing oral fluticasone propionate (5 mg four times daily) with placebo for the treatment of active distal ulcerative colitis. Sixty patients were treated for four weeks, with assessments at two and four weeks. One patient was withdrawn when she wa...
متن کاملInitial experience with golimumab in clinical practice for ulcerative colitis.
BACKGROUND Golimumab is a TNF-blocking agent indicated as a second-line therapy in ulcerative colitis. PURPOSE To research the effectiveness and safety of golimumab in patients with ulcerative colitis in clinical practice. METHODS Retrospective study of the effectiveness and safety of golimumab in patients with ulcerative colitis. All patients received golimumab 200 mg subcutaneously at wee...
متن کاملEvaluation of low doses of Azathioprine in reducing relapse and corticosteroid dependence in patients with Ulcerative Colitis
Background and Aim: Ulcerative Colitis is an idiopathic inflammatory bowel disease that is common in adults. Although corticosteroids are the most effective preservative treatment for Ulcerative Colitis. However, due to the dependence of these drugs and their serious complications, the use of an immunosuppressive drug or surgery should be taken seriously. Thus the aim of the study was the evalu...
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ژورنال
عنوان ژورنال: Current Therapeutic Research
سال: 2004
ISSN: 0011-393X
DOI: 10.1016/s0011-393x(04)80097-3